About
I’m a bioinformatics leader and independent consultant with over a decade of experience building genomic data platforms, validated clinical pipelines, and multi-omic analysis tools for biotech and precision medicine.
I currently serve as VP Bioinformatics at DataXight, where I lead delivery of validated bioinformatics pipelines, multi-omic data products, and ML environments for pharma R&D and clinical genomics. Through my consultancy, Et al Bio, I work with organizations including Google, Stanford Medicine, BioCartis, and DNAnexus.
Previously, I held leadership roles at Caris Life Sciences, Karius, DNAnexus, and UCSF, where I built and managed teams delivering CAP/CLIA validated assays, cloud-scale data infrastructure, and enterprise genomics products. I created CNVkit, a widely adopted copy number variant caller, and am a major contributor to Biopython.
Services
- Clinical bioinformatics – NGS pipeline development, analytical validation, CAP/CLIA/FDA regulatory strategy
- Multi-omic data platforms – Cloud architecture, data lakehouse design, workflow orchestration
- Genomic analysis – Variant interpretation, biomarker discovery, transcriptomics, single-cell, proteomics
- Synthetic biology & advanced therapeutics – AAV characterization, CRISPR edit validation, cell and gene therapy support
- AI/ML for life sciences – GPU-accelerated environments, structural biology, drug target validation
- Technical strategy – Team building, vendor evaluation, platform selection
Recent Posts
- Are you really vibe-coding CNVkit? – March 30, 2026
Clinical considerations for bioinformatics development with AI coding agents.